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Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure
Heart Failure Reviews, 09/22/09
Rehsia NS et al. – Vasopressin antagonists such as a non–selective antagonist, conivaptan, as well as V2 selective antagonist, tolvaptan, may prove highly valuable for the therapy of this condition. Since most of the existing interventions are helpful in treating patients with congestive heart failure only partially, there appears to be a real challenge for developing some combination therapy for the treatment of congestive heart failure.
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