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A High Fat Diet Increases Adiposity but Maintains Mitochondrial Oxidative Enzymes without Affecting Development of Heart Failure with Pressure Overload
Heart And Circulatory Physiology, 09/24/09
Chess DJ et al. – A high–fat diet did not worsen cardiac hypertrophy or left ventricular chamber enlargement despite increases in fat mass and insulin and leptin concentrations. Further, a high–fat diet preserved MCAD and citrate synthase activities during pressure overload, suggesting that it may help maintain mitochondrial oxidative capacity in failing myocardium.
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