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Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin
Heart And Circulatory Physiology, 09/15/09
Busche MN et al. – The results demonstrate MI/R–induced complement activation, inflammation and subsequent tissue injury require both IgM and MBL. Thus, MBL–dependent activation of the lectin pathway may not be completely 'antibody–independent' in I/R models.
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