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Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells
Heart And Circulatory Physiology, 09/15/09
Ungvari ZI et al. – The authors propose that resveratrol, via a pathway that involves activation of SIRT1 and up–regulation of antioxidant defense mechanisms, attenuates mitochondrial ROS production, suggesting the potential for new treatment approaches targeting endothelial mitochondria in metabolic diseases.
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