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AMP-activated protein kinase confers protection against TNF-alpha-induced cardiac cell death
Cardiovascular Research, 09/15/09
Kewalramani G et al. – The data demonstrate that although DEX and MET are used as anti–inflammatory agents or insulin sensitizers, respectively, their common property to phosphorylate AMPK promotes cardiomyocyte cell survival through its regulation of Bad and the mitochondrial apoptotic mechanism.
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