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Treatment with spironolactone for 24 weeks decreases the level of matrix metalloproteinases and improves cardiac function in patients with chronic heart failure of ischemic etiology
Canadian Journal of Cardiology, 09/14/09
Li MJ et al. – Biomarkers of collagen degradation were elevated and correlated with depressed heart function; spironolactone may partially reverse the dysregulation in collagen metabolism.
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Today in Heart Failure...keeping you current
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Clinical Research in Cardiology, 11/30/09
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