Cardiology Medical News about mitral valve prolapse disease; valve degeneration

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Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease
Cardiovascular Pathology, 09/10/09

Mahimkar R et al. – This report demonstrates that increased activity of a single enzyme, MMP–2, within a transgenic context reproduces many of the features of the human MVP syndrome. The cardiac–specific MMP–2 transgenic mouse potentially provides a unique experimental platform for the evaluation of nonsurgical therapies based on the underlying pathophysiology of this disease.

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Comparison of Cardiac Computed Tomographic Angiography to Transesophageal Echocardiography for Evaluation of Patients With Native Valvular Heart Disease
The American Journal of Cardiology, 11/10/09 Relevance Score: 88%

Mitral valve prolapse and abnormalities of haemostasis in children and adolescents with migraine with aura and other idiopathic headaches: a pilot study
Acta Neurologica Scandinavica, 10/06/09 Relevance Score: 88%

Mitral valve disease as well as uncommon extensive epipericardial and intramyocardial calcification secondary to massive mitral annular calcification
European Journal of Echocardiography, 10/22/09 Relevance Score: 82%

A Framework for Systematic Characterization of the Mitral Valve by Real-Time Three-Dimensional Transesophageal Echocardiography
Journal of The American Society of Echocardiography, 10/09/09 Relevance Score: 82%

Long-term follow-up of mitral valve regurgitation—Importance of mitral valve pathology and left ventricular function on survival
International Journal of Cardiology, 10/08/09 Relevance Score: 81%