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Your Article Summary
Kappa and delta opioid receptor signaling is augmented in the failing heart
Journal of Molecular and Cellular Cardiology, 09/08/09
Bolte C et al. – The cardiomyopathy–induced failing heart experiences increased cardiac depressant effects following opioid receptor stimulation which could exacerbate diminished cardiac function in end–stage heart failure. As cardiac function is already depressed in heart failure patients, administration of opioids could exacerbate the degree of cardiac dysfunction and worsen disease progression.
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Today in Heart Failure...keeping you current
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