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The Phosphorylation Motif at Serine 225 Governs the Localization and Function of Sphingosine Kinase 1 in Resistance Arteries
Arteriosclerosis, Thrombosis, and Vascular Biology, 09/04/09
Lidington D et al. – Translocation and precise subcellular positioning of Sk1 is essential for full Sk1 function; and two distinct S1P pools, proposed to be intra– and extracellular, contribute to the maintenance of vascular tone.
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