Cardiology Medical News about Down syndrome;congenital heart defects

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Evaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects
American Journal of Medical Genetics, 09/08/09

Carneiro Brandalize AP et al. – Maternal 677T allele may be associated with an increased occurrence of CHD in children with DS and the authors anticipate that women who carry this polymorphism would benefit from periconceptional folic acid supplementation.

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Catastrophic antiphospholipid syndrome in a patient with Down syndrome
Lupus, 10/05/09 Relevance Score: 69%

Ethnic differences in considerations whether or not to participate in prenatal screening for Down syndrome
Prenatal Diagnosis, 10/21/09 Relevance Score: 68%

Ductus venosus pulsatility index as an antenatal screening marker for Down's syndrome: use with the Combined and Integrated tests
Journal of Medical Screening, 10/07/09 Relevance Score: 68%

First-trimester Down syndrome screening in women younger than 35 years old and cost-effectiveness analysis in Taiwan population
Journal of Evaluation in Clinical Practice, 10/07/09 Relevance Score: 68%

Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndrome
Prenatal Diagnosis, 10/22/09 Relevance Score: 67%