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The Role of the Nuclear Lamins in the Pathogenesis of Heart Failure in Patients Undergoing Cardiac Transplantation
Transplantation Proceedings, 09/09/09
Cortes R et al. – Hearts with ICM or DCM showed different alterations in the nuclear morphology of cardiomyocytes; ICM patients had decreased lamin C, whereas DCM patients had increased lamin A. These changes affecting nuclear structure and function may have prognostic implications, for cardiomyopathy etiology.
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