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See Latest ArticlesHyperhomocysteinemia, intima-media thickness and C677T MTHFR gene polymorphism: A correlation study in patients with cognitive impairment
Atherosclerosis, 09/02/09
Gorgone G et al. – The findings suggest that TT677 MTHFR genotype promotes plasma homocysteine increase which in turn may favour intima–media thickening in patients with cognitive impairment. Hcy may promote neuronal damage through multiple mechanisms, including a micro–vascular damage, mediated by IMT increase, and a direct neuro–toxic effect.
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