Cardiology Medical News about bilirubin levels

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Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels—The Framingham Heart Study
Atherosclerosis, 09/03/09

Lin JP et al. – The studies suggest that UGT1A1 may be the major gene with strong effects on bilirubin levels and the TA–repeat polymorphism might be the key polymorphism within the gene controlling bilirubin levels. Since this polymorphism has a high frequency and a substantial impact on the development of CVD, the gene might be an important drug target.

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