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An Induction in Hepatic HDL Secretion Associated with Reduced ATPase Expression
American Journal of Pathology, 09/02/09
Pandey NR et al. – Linoleic acid–phospholipids stimulate high–density lipoprotein (HDL) net secretion from liver cells by blocking the endocytic recycling of apoA–I. Experiments were undertaken to determine whether apoA–I accumulation in the cell media is associated with membrane ATPase expression. The data show that an linoleic acid–phospholipid induced stimulation in hepatic HDL secretion is related to the expression and function of membrane ATP metabolizing proteins.
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