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JAK Redux - A Second Look at the Regulation and Role of JAKs in the Heart
Heart And Circulatory Physiology, 09/04/09
Kurdi M et al. – The regulation of JAKs in the heart, once touted as the paragon of simplicity, is proving rather complicated indeed, requiring a second look. It is the contention that a better understanding of the regulation of this kinase family that is implicated in cardiac protection could translate into effective therapeutic strategies for preventing myocardial damage or repairing the injured heart.
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