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See Latest ArticlesCardiac pathology exceeds skeletal muscle pathology in two cases of limb-girdle muscular dystrophy type 2I
Muscle & Nerve, 08/31/09
Margeta M et al. – The authors describe two patients with LGMD–2I who developed severe congestive heart failure that required cardiac transplantation. The dystrophic pathology and impairment of alpha–dystroglycan glycosylation were severe in the heart but mild in skeletal muscle, underscoring the lack of correlation between cardiac and skeletal muscle involvement in some LGMD–2I patients.
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