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See Latest ArticlesHigh Serum Levels of Procollagen Type III-N-terminal Amino Peptide in Patients with Congenital Heart Disease
Heart, 08/25/09
Sugimoto M et al. – The increased serum PIIIP levels in proportion with the severity of ventricular load or cyanosis suggest enhanced myocardial synthesis of collagen type III in patients with CHD. Suppression of PIIIP level by ACEI suggests the involvement of the renin–angiotensin–aldosterone system in myocardial fibrosis. These data provide the basis for the development of new diagnostic and therapeutic strategies in patients with CHD.
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