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Pappone C et al. – This study, for the first time, reveals the prevalence of latent BrS in patients with new–onset lone AF, which may precede VT/VF. Persistence of type 1 and ventricular tachyarrhythmias inducibility represents a marker of electrical instability leading to sudden death.

Exclusive Author Commentary
Vincenzo Santinelli, 08/27/09

Our experience over the years indicates that new onset atrial fibrillation particularly in young adults should not be underestimated and treated with class 1C antiarrhythmic drugs, as common clinical practice, without considering the possibility of a latent Brugada syndrome.

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