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The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health Study
Nutrition, Metabolism & Cardiovascular Diseases, 08/25/09
Junyent M et al. – The gene–gene interactions reported in the present study support the hypothesis that the effect of ABCG5/G8 genetic variants on HDL–C concentrations is dependent on ABCA1 expression. Replication of these analyses to further populations, particularly with low HDL–C, is clearly warranted.
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