Cardiology Medical News about left main coronary artery, stent, coronary artery bypass surgery, coronary artery disease

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A meta-analysis of 3,773 patients treated with percutaneous coronary intervention or surgery for unprotected left main coronary artery stenosis
JACC - Journal of the American College of Cardiology: Cardiovascular Interventions, 08/24/09

Naik H et al. – Findings show no difference in mortality or major adverse cardiovascular or cerebrovascular events, for up to 3 yrs, between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for treatment of unprotected left main coronary artery (ULMCA) stenosis. However, PCI pts had a significantly higher risk of target vessel revascularization. In select pts with ULMCA stenosis, PCI is emerging as an acceptable option.

Methods

Study to understand the total weight of evidence regarding outcomes in CABG vs PCI in ULMCA stenosis
Databases search for clinical studies that reported outcomes after PCI and CABG for treatment of ULMCA stenosis

Results

Identification of 10 studies with a total of 3,773 pts
Meta-analysis: death, myocardial infarction, and stroke (major adverse cardiovascular or cerebrovascular events) similar in PCI- and CABG-treated pts at 1, 2, and 3 yrs
Target vessel revascularization significantly higher in PCI group at 1, 2, and 3 yrs
No difference in mortality in PCI- vs CABG-treated pts at 1, 2, and 3 yrs

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Comparison of Two-Year Outcomes in Patients Undergoing Isolated Coronary Artery Bypass Grafting With and Without Peripheral Artery Disease
The American Journal of Cardiology, 11/09/09 Relevance Score: 100%

Three-Year Outcomes After Sirolimus-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Disease. Insights From the j-Cypher Registry
Circulation, 11/02/09 Relevance Score: 100%

Survival of patients on dialysis having off-pump versus on-pump coronary artery bypass surgery in the United States
The Journal of Thoracic and Cardiovascular Surgery, 10/27/09 Relevance Score: 100%

Early and Long-Term Results of Unprotected Left Main Coronary Artery Stenting: The LE MANS (Left Main Coronary Artery Stenting) Registry
JACC - Journal of the American College of Cardiology, 10/12/09 Relevance Score: 100%