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See Latest ArticlesUsefulness of the index of microcirculatory resistance for invasively assessing myocardial viability immediately after primary angioplasty for anterior myocardial infarction
European Heart Journal, 08/19/09
Lim HS et al. – The index of microcirculatory resistance (IMR), a new index representing microvascular integrity, is a reliable early on-site determinant of myocardial viability and left ventricular (LV) recovery after primary stenting for acute myocardial infarction (AMI).
Methods- Study of IMR usefulness to predict myocardial viability and LV function recovery in AMI
- Successful primary percutaneous coronary intervention in 40 pts with anterior AMI IMR
- Measurement by pressure-temperature sensor-tipped coronary guidewire
- Myocardial viability quantified by 18F-fluorodeoxyglucose (FDG) positron emission tomography in 38 pts
- Echocardiographic regional wall motion analyzed to calculate anterior wall motion score (A-WMS) and % change in A-WMS after revascularization and at 6-mo follow-up
- IMR correlated significantly with regional myocardial FDG uptake and demonstrated significant correlation with percent change in A-WMS
- Area under the receiver operating curve of IMR for predicting LV function recovery: 0.89
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