Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesClinical value of noninducibility by high-dose isoproterenol versus rapid atrial pacing after catheter ablation of paroxysmal atrial fibrillation
Journal of Cardiovascular Electrophysiology, 08/17/09
Crawford T et al. – Response to isoproterenol after catheter ablation of paroxysmal atrial fibrillation (PAF) more accurately predicts clinical outcome than the response to rapid atrial pacing (RAP).
Methods- Study to determine the relative clinical value of noninducibility of AF by isoproterenol (ISO) and by RAP in pts with PAF
- Escalating-dose ISO: 5, 10, 15, and 20 microg/min in 112 pts (age 56 ± 13 yrs) with PAF before radiofrequency catheter ablation
- Antral pulmonary vein (PV) isolation (APVI), then ablation of complex fractionated atrial electrograms (CFAEs) as needed to stop AF and render AF noninducible in response to ISO
- Induction of AF in 97 of 112 pts (87%) at mean dose of 15 ± 5 microg/min
- Induction of AF by RAP in remaining 14 of 15 pts
- Termination of AF during APVI in 72 of 111 pts (65%) and after APVI plus ablation of CFAEs in 11 of 111 pts (10%)
- Transthoracic cardioversion to restore sinus rhythm in remaining 28 pts (25%)
- RAP in last 61 consecutive pts noninducible by ISO: AF initiation in 20 pts (33%) and atrial flutter in 6 pts (10%)
- No additional ablation if AF inducible by RAP; targeting of atrial flutter
- At 12 ± 5 mo, freedom from recurrent AF for 63/75 pts (84%) noninducible by ISO and 2 of 8 (25%) reinducible by ISO after single ablation procedure without antiarrhythmic drugs
- AF recurred in 20 of 36 pts (56%) who required cardioversion for persistent AF after ablation
- Among the 61 pts who also had RAP, freedom from recurrent AF for 12 of 20 (60%) inducible pts and 31 of 41 (76%) not inducible by RAP
- Accuracy of noninducibility as a predictor of clinical outcome: 83% with ISO; 64% by RAP
Related Articles
Left superior vena cava conduction to the left atrium unmasked by adenosine in a patient with paroxysmal atrial fibrillation during pulmonary vein isolation
Europace, 11/17/09
Relevance Score: 99%
Pulmonary vein isolation using a novel decapolar over-the-wire mapping and ablation catheter
Expert Review of Cardiovascular Therapy, 11/17/09
Relevance Score: 99%
Results of Short-Term and Long-Term Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Using Duty-Cycled Bipolar and Unipolar Radiofrequency Energy
Journal of Cardiovascular Electrophysiology, 11/18/09
Relevance Score: 98%
Pressure-Guided Cryoballoon Isolation of the Pulmonary Veins for the Treatment of Paroxysmal Atrial Fibrillation
Journal of Cardiovascular Electrophysiology, 10/01/09
Relevance Score: 98%
The difference in autonomic denervation and its effect on atrial fibrillation recurrence between the standard segmental and circumferential pulmonary vein isolation techniques
Europace, 11/10/09
Relevance Score: 97%
Today in Interventional...keeping you current
Receive free subspecialty "5-minute updates" via email
A Novel 3-D Reconstruction System for the Assessment of Bifurcation Lesions Treated by the Mini-Crush Technique
Journal of Interventional Cardiology, 12/07/09
Prehospital 12-Lead ECG to Triage ST-Elevation Myocardial Infarction and Emergency Department Activation of the Infarct Team Significantly Improves Door-to-Balloon Times
Circulation: Cardiovascular Interventions, 12/03/09
Relationship Between Baseline Inflammatory Markers, Antiplate let Therapy, and Adverse Cardiac Events After Percutaneous Coronary Intervention
Circulation: Cardiovascular Interventions, 11/24/09
Sponsor
Article Search
Sponsor
Sponsor