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Glycogen synthase kinase-3-beta is activated by matrix metalloproteinase-2 mediated proteolysis in cardiomyoblasts
Cardiovascular Research, 08/17/09
Kandasamy AD et al. – GSK–3–beta may be a target of MMP–2 and its cleavage by MMP–2 enhances its kinase activity. MMP–2 may cleave off the N–terminal of GSK–3–beta where the inhibitory phosphorylation of serine–9 occurs. MMP–2–mediated augmentation of GSK–3–beta kinase activity may contribute to cardiac injury resulting from enhanced oxidative stress.
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Reduced expression of the sodium-calcium exchanger in adult cardiomyocytes via adenovirally delivered shrna results in resistance to simulated ischemic injury
Heart And Circulatory Physiology, 12/11/09
Progressive Muscle Metaboreflex Activation Gradually Decreases Spontaneous Heart Rate Baroreflex Sensitivity During Dynamic Exercise
Heart And Circulatory Physiology, 12/11/09
Over-expression of hepatocyte growth factor in smooth muscle cells regulates endothelial progenitor cells differentiation, migration and proliferation
International Journal of Cardiology, 12/10/09
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