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See Latest ArticlesCardiac Repolarization Indices in Epilepsy Patients
Cardiology, 08/14/09
Neufeld G et al. – Changes in QT interval duration (QTmax c, QTmin c) and dispersion (QTD c) are higher in epilepsy pts vs controls. Q-T interval may be related to disease duration but is unrelated to pt age or recent reported seizure frequency.
Methods- Investigation of whether QTmax c, QTmin c, and QTD c occur in epileptic pts
- Retrospective study of 40 consecutive Epilepsy Monitoring Unit pts (age 36.1 ± 22.2 yrs) who had seizure disorder for 14.0 ± 12.2 and 60 age-matched non-epileptic controls (age 38.0 ± 15.6 yrs)
- Calculation of Q-T intervals from single 12-lead ECG
- Higher QTmax c and QTD c and lower QTmin c in epilepsy pts vs controls
- QTmax c significantly correlated with disease duration before, but not after age correction
- Neither age nor reported recent seizure frequency correlated with any repolarization index
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