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The Role of RAS Modification for Primary and Secondary Stroke Prevention
Postgraduate Medicine, 07/29/09
Fintel DJ – Clinical trial results indicate that the choice of antihypertensive agent can be a determinant of stroke protection, independent of blood pressure (BP) reduction. Angiotensin–converting enzyme inhibitors (ACE–Is) are effective for BP control and stroke protection, but their use may be limited by patient tolerability. Angiotensin receptor blockers appear to provide similar BP control compared with ACE–Is and may also offer the clinician the added benefit of primary and secondary stroke prevention, with the potential for fewer tolerability issues.
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