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See Latest ArticlesUtility of Routine Immunofluorescence Staining for C4d in Cardiac Transplant Recipients
The Journal of Heart and Lung Transplantation, 07/28/09
Gupta S et al. – Positive C4d immunofluorescence staining on EMB specimens was associated with ACR, reduced allograft function, a positive retrospective crossmatch, and the presence of DSA after transplantation. The latter 2 observations support the contention that C4d deposition is a marker of antibody–mediated rejection. Routine evaluation of C4d staining is feasible in the clinical setting and may identify variable patterns of rejection.
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