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RhoA/ROK Pathway Related to the Mechanism of Higher Susceptibility to Spasm in RA Than in IMA
Journal of Cardiac Surgery, 07/28/09
Kun X et al. – The expression of RhoA/Rho kinase mRNA and protein and function in the RA were significantly stronger than in the IMA, suggesting that RhoA/Rho kinase pathway may be one mechanism by which RA is more susceptible to spasm than IMA. Rho kinase inhibitors can be effective drug candidates to prevent and treat vasospasm.
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