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Myocardial Interstitial Fluid Inhibits Proliferation and Cardiomyocyte Differentiation in Pluripotent Embryonic Stem Cells
Heart And Circulatory Physiology, 07/28/09
Van Orman JR et al. – The results suggest that while the ischemic/infarcted environment is favorable to stem cell–mediated angiogenesis, it is hostile to cardiac myogenesis. These findings also imply that observations of mESC–mediated improvement of cardiac function after transplantation of pluripotent cells do not reflect re–muscularization.
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