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See Latest ArticlesLight-induced vs. bradykinin-induced relaxation of coronary arteries: do S-nitrosothiols act as endothelium-derived hyperpolarizing factors
Journal of Hypertension, 07/24/09
Batenburg WW et al. – Photorelaxation depends on stored S–nitrosothiols and their release/synthesis is negatively affected by endothelial nitric oxide and IKCa/SKCa. S–Nitrosothiols activate endothelial IKCa/SKCa and, via guanylyl cyclase, smooth muscle Na+–K+ ATPase. Thus, they possess all properties of a bradykinin–induced endothelium–derived hyperpolarizing factor.
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