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Kelly TN et al. – This review of 5 large trials found that, compared with conventional control, intensive glucose control reduced the risk for some cardiovascular disease (such as nonfatal myocardial infarction), did not reduce the risk for cardiovascular death or all–cause mortality, and increased the risk for severe hypoglycemia. Health care providers should focus their efforts on combining elements of lifestyle modification, glucose control that minimizes hypoglycemia, blood pressure reduction, and lipid lowering to optimally curtail the risk for CVD in patients with type 2 diabetes.

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