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Sphingosine-1-Phosphate Receptor-2 Regulates Expression of Smooth Muscle Alpha-Actin After Arterial Injury
Arteriosclerosis, Thrombosis, and Vascular Biology, 07/22/09
Grabski AD et al. – The results of this study support the hypothesis that S1P2R regulates expression of SMA after injury. The authors further conclude that transcriptional regulation of SMA by S1P in vitro requires S1P2R–dependent activation of RhoA and mobilization of calcium from intracellular calcium stores.
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