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See Latest ArticlesLoss of Cardiac Phosphoinositide 3-Kinase p110-alpha Results in Contractile Dysfunction
Circulation, 07/14/09
Lu Z et al. - PI3K p110-alpha but not p110-beta regulates the LTCC in cardiac myocytes. Decreased signaling to p110-alpha reduces the number of LTCCs on the cell surface and thus attenuates ICa,L and contractility.
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