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See Latest ArticlesImpact of the metabolic syndrome on aortic pulse pressure and ascending aortic pulsatility in patients with angiographically normal coronary arteries
Canadian Journal of Cardiology, 07/09/09
Emre A et al. – Data show that the metabolic syndrome is independently associated with increased aortic pulse pressure (PP) and ascending aortic pulsatility (AP) in pts with normal coronary arteries, suggesting aortic stiffness as a possible mechanisms for excess cardiovascular risk associated with the metabolic syndrome.
Methods- Study of the impact of the metabolic syndrome on aortic PP and ascending AP in pts with angiographically normal coronary arteries
- Assessment of 42 pts with the metabolic syndrome and 40 age-matched controls without the metabolic syndrome; normal coronary arteries for all subjects
- Diagnosis of the metabolic syndrome based on 2005 International Diabetes Federation guidelines
- Ascending AP estimated as ratio of aortic PP to mean blood pressure
- Aortic PP and ascending AP significantly higher in the metabolic syndrome group
- On multiple regression analysis, statistically independent relationships between ascending AP and fasting blood glucose, waist circumference, and systolic blood pressure
- The metabolic syndrome, as a whole, also independently associated with both ascending AP and aortic PP
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