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Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes
Journal of Molecular and Cellular Cardiology, 07/06/09
Wang H et al. - The data suggests a novel physiological role for PDE5 in restricting the effects of NOS3/sGC/PKG signaling pathway to modulating beta-AR stimulated ICa, while limiting effects on cardiac contraction.
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