Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesPulse pressure, left ventricular function and cardiovascular events during antihypertensive treatment (the LIFE study)
Blood Pressure, 07/01/09
Gerdts E et al. – During systematic antihypertensive treatment in hypertensive pts with electrocardiographic left ventricular (LV) hypertrophy, lower in-treatment pulse pressure (PP) was associated with lower in-treatment LV function and cardiac output as well as higher rate of cardiovascular events
Methods- Study of associations of in-treatment PP with LV systolic function and cardiovascular events
- Subjects: 883 pts with electrocardiographic LV hypertrophy during 4.8 yrs of randomized losartan- or atenolol-based treatment
- Echocardiographic substudy of the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study
- Both treatments similarly reduced PP
- In different multiple regression models, lower in-treatment PP independently associated with lower in-treatment LV ejection fraction, stress-corrected midwall shortening, stroke volume, and cardiac index
- In time-varying Cox regression models, 10 mmHg lower in-treatment PP associated with 28% higher rate of cardiovascular events
- Association independent of in-treatment LV mass and ejection fraction, history of ischemic heart disease, Framingham risk score and study treatment allocation
Related Articles
Sex Differences in Pulse Pressure Trends With Age Are Cross-Cultural
Hypertension, 11/17/09
Relevance Score: 69%
Beyond office sphygmomanometry: Ways to better assess blood pressure
Cleveland Clinic Journal of Medicine, 11/05/09
Relevance Score: 68%
Pulse Pressure, Prehypertension, and Mortality: The San Antonio Heart Study
American Journal of Hypertension, 11/03/09
Relevance Score: 68%
Pulse Pressure, Prehypertension, and Mortality: The San Antonio Heart Study
American Journal of Hypertension, 10/28/09
Relevance Score: 68%
High Systolic and Pulse Pressure Levels Are Associated with Better Cognitive Performance in Patients with Probable Alzheimer's Disease: A Cross-Sectional Observational Study in a Geriatric Outpatient Population
Dementia and Geriatric Cognitive Disorders, 10/23/09
Relevance Score: 67%
Today in Physiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure
European Heart Journal, 11/25/09
Temporal Responses to Intrinsically Coupled Calcium and Zinc Dyshomeostasis in Cardiac Myocytes and Mitochondria During Aldosteronism
Heart And Circulatory Physiology, 11/19/09
Pre-lesional arterial endothelial phenotypes in hypercholesterolemia: Universal ABCA1 upregulation contrasts with region-specific gene expression in vivo
Heart And Circulatory Physiology, 11/19/09
Sponsor
Article Search
Sponsor
Sponsor