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CO-releasing molecule (CORM-3)-derived CO modulates neutrophil (PMN) migration across vascular endothelium by reducing the levels of cell surface-bound elastase
Heart And Circulatory Physiology, 07/02/09
Mizuguchi S et al. - The findings indicate that in sepsis CORM3-released CO while further amplifying ROS production and degranulation of PMN concurrently reduces the levels of cell surface-bound elastase, which contributes to suppressed PMN transendothelial migration.
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