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Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
Cardiovascular Research, 06/30/09
Strande JL et al. - A single treatment of parstatin administered prior to ischaemia confers immediate cardioprotection by recruiting the Gi-protein activation pathway including p38 MAPK, ERK1/2, NOS, and KATP channels. Parstatin exerts effects on both the cardiomyocytes and the coronary circulation to induce cardioprotection. This suggests a potential therapeutic role of parstatin in the treatment of cardiac injury resulting from ischaemia and reperfusion.
Today in Clinical Pharmacology...keeping you current
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Low-Density Lipoprotein Cholesterol Reduction and Goal Achievement With Ezetimibe/Simvastatin Versus Atorvastatin or Rosuvastatin in Patients With Diabetes, Metabolic Syndrome, or Neither Disease, Stratified By National Cholesterol Education Program Risk Category
Metabolic Syndrome and Related Disorders, 11/25/09
Prevalence of Inappropriate Use of Digoxin in 136 Patients on Digoxin and Prevalence of Use of Warfarin or Aspirin in 89 Patients With Persistent or Paroxysmal Atrial Fibrillation
American Journal of Therapeutics, 11/25/09
Correlation of paramedic administration of furosemide with emergency physician diagnosis of congestive heart failure
Journal of Emergency Primary Health Care, 11/24/09
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Association of Hospital Primary Angioplasty Volume in ST-Segment Elevation Myocardial Infarction With Quality and Outcomes
JAMA, 11/25/09
Mode of arrival does not predict myocardial infarction in patients who present to the ED with chest pain
International Journal of Emergency Medicine, 11/25/09
Increased Carotid Intima Media Thickness as a Predictor of the Presence and Extent of Abnormal Myocardial Perfusion in Type 2 Diabetes Mellitus
Diabetes Care, 11/23/09
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