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The use of controlled reperfusion strategies in cardiac surgery to minimize ischaemia/reperfusion damage
Cardiovascular Research, 06/30/09
Beyersdorf F - The cardiac surgeon is in a unique position to protect the heart before ischaemia is induced and to avoid further damage during the reperfusion period. The surgeon can alter the composition of the reperfusate and the conditions of reperfusion so that the ischaemia/reperfusion injury is minimal, even after very complex procedures that require long aortic cross-clamp periods. This in turn allows him to perform a near-perfect surgical repair of the underlying disease without the pressure of time.
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