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Palmitoylation of ATP-Binding Cassette Transporter A1 Is Essential for Its Trafficking and Function
Circulation Research, 06/29/09
Singaraja RR et al. - ABCA1 is palmitoylated by the palmitoyl transferase DHHC8, and increasing DHHC8 protein results in increased ABCA1-mediated lipid efflux. Thus, palmitoylation regulates ABCA1 localization at the plasma membrane, and regulates its lipid efflux ability.
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