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Statins and prevention of atrial fibrillation in patients with heart failure
International Journal of Cardiology, 06/26/09
Liu T et al. – A review of statins and prevention of atrial fibrillation (AF) in heart failure (HF) pts summarizes recent efficacy and outcome data as well as the anti-arrhythmic mechanisms of statin in this setting.
Methods- Review of statins and prevention of AF in HF
- Statins are highly effective and widely used lipid-lowering agents in clinical practice with pleiotropic properties beyond cholesterol lowering
- Trials show reduced cardiovascular morbidity and mortality in both primary and secondary prevention with statins
- Statins may have beneficial effects on cardiovascular outcomes in HF, specifically in prevention of AF
- Anti-arrhythmic mechanisms of statins regarding AF prevention in HF patients are not fully understood
- Mechanisms may be related to pleiotropic effects: anti-inflammatory, antioxidant, atrial remodeling attenuation, ion channel stabilization, and autonomic nervous system regulation
Today in Arrhythmias/EP...keeping you current
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Acute Coronary Syndromes: Diagnosis and Management, Part I
Mayo Clinic Proceedings, 10/05/09
Acute medical management of the non-ST-segment elevation acute coronary syndromes (NSTE-ACS) in older patients
Archives of Gerontology and Geriatrics, 10/14/09
New Anticoagulants in Atrial Fibrillation
Seminars in Thrombosis and Hemostasis, 10/02/09
Today in Clinical Pharmacology...keeping you current
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New Anticoagulants in Atrial Fibrillation
Seminars in Thrombosis and Hemostasis, 10/02/09
New Anticoagulants for Atrial Fibrillation
Seminars in Thrombosis and Hemostasis, 09/15/09
Effectiveness of Two-Year Clopidogrel + Aspirin in Abolishing the Risk of Very Late Thrombosis After Drug-Eluting Stent Implantation (from the TYCOON [Two-Year ClOpidOgrel Need] Study)
The American Journal of Cardiology, 11/05/09
Today in Heart Failure...keeping you current
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Obesity-Related Cardiorenal Syndrome
The Journal of Clinical Hypertension, 10/20/09
The Atrial Fibrillation Paradox of Heart Failure
Congestive Heart Failure, 09/29/09
Prognosis in Heart Failure and the Value of Beta-blockers are Altered by the Use of Antidepressants and Depend on the Type of Antidepressants Used
Circulation: Heart Failure, 09/24/09
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