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Inflammation, Coagulation, and the Pathway to Frailty
American Journal of Medicine, 06/26/09

Kanapuru B et al. - Although chronic illnesses are common among frail elderly persons, some will develop all of the phenotypic features without a diagnosed underlying disease. It has been recognized that certain proinflammatory cytokines and coagulation factors are elevated to a greater extent in those who are frail than in age-matched nonfrail individuals. In this review, we provide an overview of current research in the biology of frailty with particular emphasis on the role of inflammatory pathways and disordered coagulation in its pathogenesis.

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Obstructive left-sided prosthetic valve thrombosis

A review of long-term prophylaxis in the rare inherited coagulation factor deficiencies
Haemophilia, 11/18/09 Relevance Score: 87%

Spectrum of inherited bleeding disorders in southern Iran, before and after the establishment of comprehensive coagulation laboratory
Blood Coagulation & Fibrinolysis, 11/03/09 Relevance Score: 87%

Activation of Endothelial and Coagulation Systems in Left Ventricular Assist Device Recipients
Annals of Thoracic Surgery, 10/13/09 Relevance Score: 87%

Heparin but not citrate anticoagulation of blood preserves platelet function for prolonged periods
Journal of Thrombosis and Haemostasis, 10/29/09 Relevance Score: 85%

Appraisal of the selectivity index in a cohort of patients treated with laser surgery for twin-twin transfusion syndrome
American Journal of Obstetrics and Gynecology, 10/26/09 Relevance Score: 84%