Cardiology

Your Article Summary

See Latest Articles

Percutaneous transvenous mitral annuloplasty: Initial human experience with a novel coronary sinus implant device
Circulation: Cardiovascular Interventions, 06/25/09

Sack S et al. – Percutaneous implantation of a novel coronary sinus mitral repair device (PTMA) is feasible and safe. Acute results show a possibly meaningful reduction of mitral regurgitation (MR) in responding pts. Sustained favorable geometric modification of the mitral annulus is reported, despite limited reduction of MR.

• Study of the safety and feasibility of permanent implantation of PTMA device
• Subjects: symptomatic (NYHA class 2 or 3) pts with primarily functional MR
• Diagnostic PTMA procedure in coronary sinus venous continuity
• Assessment of MR, then PTMA device adjustment to optimize efficacy
• PTMA implant placement attempted if MR reduction (≤1 grade)
• Echocardiographic, quality of life, and exercise capacity metrics evaluation of implanted pts

• Diagnostic PTMA study for 19 pts
• Diagnostic PTMA effective in 13 pts: MR grade 3.2±0.6 reduced to 2.0±1.0
• PTMA implants placed in 9 pts
• Uneventful removal of 4 devices (7, 84, 197, 216 days), 3 for annuloplasty surgery due to observed PTMA device migration and/or diminished efficacy
• No procedure or device-related major adverse events with permanent sequela in any diagnostic or implant pts
• Sustained reductions of mitral annulus septal-lateral dimension from 3D echo reconstruction dimensions (4.0±1.2 mm at 3 mo)

Related Articles

See all related articles

Percutaneous Mitral Annuloplasty with the VIACOR Coronary Sinus System for the Treatment of Functional Mitral Regurgitation in Heart Failure Patients. Development and Results
Herz, 10/08/09    Relevance Score: 80%

Percutaneous Mitral Valve Annuloplasty with the Carillon Mitral Contour System by Cardiac Dimensions. A Minimally Invasive Therapeutic Option for the Treatment of Severe Functional Mitral Valve Regurgitation
Herz, 10/08/09    Relevance Score: 80%

The Role of Imaging in Percutaneous Mitral Valve Repair
Herz, 10/07/09    Relevance Score: 80%

Insight Into the Dynamics of the Coronary Sinus/Great Cardiac Vein and the Mitral Annulus
Circulation: Cardiovascular Interventions, 11/16/09    Relevance Score: 79%

Hybrid Therapy of Radiofrequency Catheter Ablation and Percutaneous Transvenous Mitral Commissurotomy in Patients With Atrial Fibrillation and Mitral Stenosis
Journal of Cardiovascular Electrophysiology, 10/13/09    Relevance Score: 79%

Today in Interventional...keeping you current

Receive free subspecialty "5-minute updates" via email

A Novel 3-D Reconstruction System for the Assessment of Bifurcation Lesions Treated by the Mini-Crush Technique
Journal of Interventional Cardiology, 12/07/09

Prehospital 12-Lead ECG to Triage ST-Elevation Myocardial Infarction and Emergency Department Activation of the Infarct Team Significantly Improves Door-to-Balloon Times
Circulation: Cardiovascular Interventions, 12/03/09

Prognostic Impact of Periprocedural Bleeding and Myocardial Infarction After Percutaneous Coronary Intervention in Unselected Patients
JACC - Journal of the American College of Cardiology: Cardiovascular Interventions, 11/20/09

 See all of Interventional

Today in Valvular Disease...keeping you current

Receive free subspecialty "5-minute updates" via email

Judicious use of transthoracic echocardiography in infective endocarditis screening
Canadian Journal of Cardiology, 12/10/09

Midterm results of transapical aortic valve replacement via real-time magnetic resonance imaging guidance
The Journal of Thoracic and Cardiovascular Surgery, 12/10/09

Replacement of the Aortic Valve in a Patient with Mucolipidosis III
Cardiology in the Young, 12/07/09

 See all of Valvular Disease