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Lau DCW - This review appraises the evidence in support of or against recognizing metabolic syndrome as a clinical condition that requires therapeutic intervention. Proper evaluation of cardiovascular disease risk should start with consideration of traditional risk factors using validated tools, such as the short-term 10-year Framingham risk score. Individuals with abdominal obesity should be further assessed for associated cardiometabolic risks. Global cardiovascular disease risk should take into consideration not only short-term but also lifetime risks.

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