Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesEffect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults
The American Journal of Cardiology, 06/23/09
Viljanen APM et al. – Weight reduction decreases myocardial fatty acid uptake in parallel with myocardial mass and cardiac work. These results show that the increased fatty acid uptake found in the hearts of obese pts can be reversed by weight loss.
Methods- Study of how weight loss influences myocardial metabolism and cardiac work in obese adults
- Subjects: 34 obese (mean body mass index 33.7 ± 0.7 kg/m2) but otherwise healthy pts
- Consumption of a very low calorie diet for 6 wks
- Measurement of cardiac substrate metabolism and work before/after diet
- Fluorine-18-fluoro-6-thia-heptadecanoic acid and positron emission tomography to measure myocardial fatty acid uptake in 18 pts
- Fluorine-18-2-fluoro-2-deoxyglucose to measure myocardial glucose uptake in 16 pts
- Magnetic resonance imaging to measure myocardial structure and cardiac function
- Consumption of very low calorie diet decreased weight (-11.2 ± 0.6 kg)
- Myocardial fatty acid uptake decreased from 4.2 ± 0.4 to 2.9 ± 0.2 micromol/100 g/min
- Myocardial mass decreased by 7%
- Cardiac work decreased by 26%
- Whole-body insulin sensitivity increased by 33%
- Insulin-stimulated myocardial glucose uptake remained unchanged
- Myocardial triglyceride content decreased by 31%
Today in Myocardium/Pericardium...keeping you current
Receive free subspecialty "5-minute updates" via email
Predictors of cardiovascular events in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study
Blood Pressure, 12/11/09
Doxorubicin Cardiomyopathy
Cardiology, 12/11/09
Evidence of clinical practice heterogeneity in the use of implantable cardioverter-defibrillators in heart failure and post–myocardial infarction left ventricular dysfunction: Findings from IMPROVE HF
Heart Rhythm, 12/11/09
Today in Physiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Heart rate turbulence assessment in systemic sclerosis: The role for the detection of cardiac autonomic nervous system dysfunction
Rheumatology, 12/11/09
Reduced expression of the sodium-calcium exchanger in adult cardiomyocytes via adenovirally delivered shrna results in resistance to simulated ischemic injury
Heart And Circulatory Physiology, 12/11/09
Progressive Muscle Metaboreflex Activation Gradually Decreases Spontaneous Heart Rate Baroreflex Sensitivity During Dynamic Exercise
Heart And Circulatory Physiology, 12/11/09
Sponsor
Article Search
Sponsor
Sponsor