Cardiology Medical News

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death

3. The Job Market for 2008-2009: Compensation

4. Renal Artery Stenosis

5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Meta-analysis of diagnostic efficacy of 64-slice computed tomography in the evaluation of coronary in-stent restenosis
The American Journal of Cardiology, 06/22/09

Kumbhani DJ et al. – Results show that 64-slice computed tomography (CT) can detect (high sensitivity and specificity) or exclude in-stent restenosis (ISR) (high negative predictive value [NPV]) with; however, precise quantification of ISR is inaccurate (low positive predictive value [PPV]). Efficacy estimates are even lower with inclusion of nonassessable segments; thus stress imaging remains the most acceptable noninvasive technique for diagnosis of ISR.

Methods

Meta-analysis for diagnostic efficacy of 64-slice CT in evaluation of ISR
Inclusion of studies that used 64-slice CT for evaluation of coronary ISR
Pool of efficacy estimates across studies using random-effects models

Results

Optimal noninvasive assessment by 64-slice CT of coronary artery disease
Various artifacts limit evaluation of stented coronary segments
Of 14 studies, 895 pts: 1,447 stents, mean diameter 3.1 mm
Of 1,447 stents, 1,231 (91.4%) stents adequately assessed by 64-slice CT
Overall 91% sensitivity; 91% specificity; 68% PPV; 98% NPV
On inclusion of nonassessable segments, overall sensitivity and specificity decreased to 87% and 84%, with PPV of 53% and an NPV of 97%, respectively