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See Latest ArticlesEndothelin-1 Is a Key Mediator of Coronary Vasoconstriction in Patients with Transplant Coronary Arteriosclerosis
Circulation: Heart Failure, 06/18/09
Larose E et al. - This study shows for the first time in humans that ET-1 is an important mediator of coronary vasoconstriction in TCA and accounts for >50% of the increased vasomotor tone. Therapeutic targeting of ET-1 may retard the development of TCA.
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