Cardiology Medical News about atrial fibrillation;severe chronic mitral regurgitation;mitral valve repair

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Ventricular reverse remodeling early after mitral valve repair for severe chronic mitral regurgitation with atrial fibrillation
Cardiology, 06/15/09

Song BG et al. – Preoperative lower N-terminal B-type natriuretic peptide (NT-proBNP) levels and younger age may predict by left ventricular reverse remodeling (LVRR) early after surgical correction of chronic mitral regurgitation (MR) with atrial fibrillation (AF).

Methods

Study of the relation of clinical, echocardiographic findings and NT-proBNP to LVRR early after valve repair for severe chronic MR concomitant with modified maze procedure for AF
Retrospective evaluation of 60 pts surgically treated for severe chronic MR and AF
Plasma NT-proBNP and echocardiographic measurements before surgery, before discharge and 12 mo after surgery
Echocardiogram additionally performed at 6 mo
LVRR assessed by regression of LV mass index (LVMI) using echocardiography

Results

LVRR group: 52 pts (87%), defined as a postoperative reduction in LVMI
Remaining pts classified in non-LVRR group
Non-LVRR group older, had significantly higher ratio of hypertensive pts, higher NT-proBNP levels, and lower ejection fraction vs LVRR group
In multivariate analysis, age and NT-proBNP levels were independent predictors of LVRR

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