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Diabetic cardiomyopathy – a distinct disease
Best Practice & Research Clinical Endocrinology & Metabolism, 06/19/09
Khavandi K et al. - The natural history is characterized by a latent subclinical period, during which there is evidence of diastolic dysfunction and left ventricular hypertrophy, before overt clinical deterioration and systolic failure ensue. These clinical findings have been supported by a growing body of experimental data which support the notion that diabetes inflicts a direct insult to the myocardium, with cellular, structural and functional changes manifest as the diabetic myocardial phenotype.
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