Cardiology Medical News about obstructive sleep apnea;hypertension

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Hypertension in obstructive sleep apnea: Risk and therapy
Expert Review of Cardiovascular Therapy , 06/12/09

Das AM et al. – A review focuses on the pathophysiology and causal relationship between obstructive sleep apnea (OSA) and hypertension, as well as the cardiovascular effects of treatment of OSA.

Methods

Review of the risk of and therapy for hypertension in OSA

Results

OSA: risk factor for developing hypertension
Pathophysiologic mechanism: distinctive pattern of intermittent hypoxia in OSA
Pattern increases sympathetic tone, oxidative stress, inflammation and endothelial dysfunction
These processes may lead to persistent elevation of blood pressure beyond obstructive events
OSA: key part of workup for hypertensive pts
Treatment of OSA with continuous positive airway pressure affects hypertension control and risk reduction of cardiovascular diseases

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Upper Esophageal Sphincter and Gastroesophageal Junction Pressure Changes Act to Prevent Gastroesophageal and Esophagopharyngeal Reflux during Apneic Episodes in Patients with Obstructive Sleep Apnea
Chest, 11/17/09 Relevance Score: 83%

Sleep and Sleep Disorders in Chronic Obstructive Pulmonary Disease
Respiration, 11/12/09 Relevance Score: 83%

Impact of CPAP treatment on cardiac biomarkers and pro-BNP in obstructive sleep apnea syndrome
Sleep and Breathing, 10/21/09 Relevance Score: 83%

Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death
Sleep and Breathing, 10/06/09 Relevance Score: 83%

Screening for Obstructive Sleep Apnea on the Internet: Randomized Trial
American Journal of Medicine, 10/02/09 Relevance Score: 83%