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Tourneau TL et al. - This population-based comprehensive study of anticoagulation and TE post-MVR shows that in these closely anticoagulated patients, anticoagulation intensity is highly variable and not associated with TE incidence post-MVR. Higher anticoagulation intensity is linked to higher variability and thus to bleeding. The MVR-ball design is associated with higher TE rates notwithstanding higher anticoagulation intensity and should be retired worldwide.

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